abstract：:The so-called on- and off-cells of the rostral ventromedial medulla (RVM) send their axons to the spinal dorsal horn. Activation of on-cells precedes and coincides with a facilitation, and activation of off-cells coincides with an inhibition, of withdrawal reflexes elicited by noxious agents. Considerable evidence sup...

journal_title：Brain research

authors： Salas R,Ramirez K,Tortorici V,Vanegas H,Vazquez E

更新日期：2018-05-01 00:00:00

abstract：:MicroRNAs (miRNAs) are a class of non-coding small RNAs that regulate the expression of target genes. They derive from pre-miRNAs that are enzymatically processed by dicer to ∼22 nucleotide mature miRNAs. Members of the pre-miRNA lethal-7 (let-7) are known to regulate cell proliferation and apoptosis. Here, we showed ...

journal_title：Brain research

authors： Lv J,Zeng Y,Qian Y,Dong J,Zhang Z,Zhang J

更新日期：2018-04-15 00:00:00

abstract：:Ischemic stroke brings a huge family and social burden. Although the reperfusion of ischemic cerebral tissue is the most important way to rescue ischemic stroke, ischemia-reperfusion (I/R) injury further results in brain damage and even lead to death. Recent studies demonstrated that Tongxinluo (TXL) helps to protect ...

journal_title：Brain research

authors： Yu Z,Cai M,Li X,Zhang J,Wu T,Yang F,Zhu W,Xiang Y,Zhang W,Xiang J,Cai D

更新日期：2018-04-15 00:00:00

abstract：:Interactive-activation models posit that visual word recognition involves co-activation of orthographic neighbors (e.g., note, node) and competition among them via lateral inhibitory connections. Behavioral evidence of this lexical competition comes from masked priming paradigms, in which target words elicit slower re...

journal_title：Brain research

authors： Meade G,Grainger J,Midgley KJ,Emmorey K,Holcomb PJ

更新日期：2018-04-15 00:00:00

abstract：:Neurogenesis might influence oligodendrogenesis and selectively instruct myelination in the mammalian brain. Running exercise could induce neurogenesis and protect the myelin sheaths in the dentate gyrus of AD mice. It is unclear whether running exercise can protect myelin sheaths in the absence of neurogenesis in the...

journal_title：Brain research

authors： Chao FL,Zhang L,Zhang Y,Zhou CN,Jiang L,Xiao Q,Luo YM,Lv FL,He Q,Tang Y

更新日期：2018-04-01 00:00:00

abstract：:The early electrophysiological phenomena linked to systemic inflammation are largely underexplored. We developed here local field analyses to detect prodromal oscillatory abnormalities. We identified early band-specific patterns in local field potential recorded from freely-moving rats injected intraperitoneally with ...

journal_title：Brain research

authors： Mamad O,Islam MN,Cunningham C,Tsanov M

更新日期：2018-02-15 00:00:00

abstract：:Gulf War Illness (GWI) is a chronic disease that affects the 1991 Gulf War (GW) veterans for which treatment is lacking. It has been hypothesized that drugs used to protect military personnel from chemical attacks and insects during the war: pyridostigmine bromide (PB),N, N-diethyl-m-toluamide (DEET), and permethrin (...

journal_title：Brain research

authors： Carreras I,Aytan N,Mellott T,Choi JK,Lehar M,Crabtree L,Leite-Morris K,Jenkins BG,Blusztajn JK,Dedeoglu A

更新日期：2018-02-15 00:00:00

abstract：:Recent research suggests that attributing human movement to ambiguous and static Rorschach stimuli (M responses) is associated with EEG mu suppression, and that disrupting the left inferior gyrus (LIFG; a putative area implicated in mirroring activity) decreases the tendency to see human movement when exposed to the R...

journal_title：Brain research

authors： Ando' A,Pineda JA,Giromini L,Soghoyan G,QunYang,Bohm M,Maryanovsky D,Zennaro A

更新日期：2018-02-01 00:00:00

abstract：:Mouse VD-hemopressin(α) (VD-Hpα) is an undecapeptide that selectively activates CB1 cannabinoid receptor in in vitro functional tests, and exerts CB1-mediated central antinociception in the mouse tail-flick assay. The aim of the present study was to further investigate the analgesic properties of supraspinal mouse VD-...

journal_title：Brain research

authors： Zheng T,Zhang R,Zhang T,Zhang MN,Xu B,Song JJ,Li N,Tang HH,Wang P,Wang R,Fang Q

更新日期：2018-02-01 00:00:00

abstract：:A hemodynamic mechanism has long been assumed to play an important role in watershed infarction. In recent years, however, clinical evidence has indicated that an embolic mechanism is involved. The mechanism by which emboli are trapped preferentially in watershed areas remains unclear. In the present study, we develop...

journal_title：Brain research

authors： Tsukada N,Katsumata M,Oki K,Minami K,Abe T,Takahashi S,Itoh Y,Suzuki N

更新日期：2018-01-15 00:00:00

abstract：:Chronic developmental exposure to ethanol can lead to a wide variety of teratogenic effects, which in humans are known as fetal alcohol spectrum disorders (FASD). Individuals affected by FASD may exhibit persistent impairments to cognitive functions such as learning, memory, and attention, which are highly dependent o...

journal_title：Brain research

authors： Louth EL,Luctkar HD,Heney KA,Bailey CDC

更新日期：2018-01-01 00:00:00

abstract：:The amygdala is a bilateral temporal lobe brain region which plays an important role in emotional processing. Past studies on the amygdala have shown hemispheric differences in amygdalar processes and responses associated with specific pain and fear behaviors. Despite the functional differences in the amygdala, few st...

journal_title：Brain research

authors： Butler RK,Oliver EM,Fadel JR,Wilson MA

更新日期：2018-01-01 00:00:00

abstract：:Power spectral analysis of the electroencephalogram (EEG) is a non-invasive method to examine infant brain maturation. Preterm fetal growth restricted (p-FGR) neonates display an altered EEG power spectrum compared to appropriate-for-gestational-age (AGA) peers, suggesting delayed brain maturation. Longitudinal studie...

journal_title：Brain research

authors： Cohen E,Wong FY,Wallace EM,Mockler JC,Odoi A,Hollis S,Horne RSC,Yiallourou SR

更新日期：2018-01-01 00:00:00

abstract：:The functions of the claustrum are not well understood. Few studies explore its electrophysiological properties in awake animals. Here, we address this lacuna by recording spontaneous local field potential (LFP) activity in the anterior claustrum of rats freely exploring open field environments under differing conditi...

journal_title：Brain research

authors： Jankowski MM,Islam MN,O'Mara SM

更新日期：2017-12-15 00:00:00

abstract：:Alzheimer's disease is a common age associated neurodegenerative disorder associated with an elevated risk of seizures that may be fundamentally connected to cognitive dysfunction. We used 4-9month-old mice of the APP/PS1 mouse model of Alzheimer's disease to study the presence of epileptiform-like discharges and to e...

journal_title：Brain research

authors： Reyes-Marin KE,Nuñez A

更新日期：2017-12-15 00:00:00

abstract：:Response conflict can be induced by priming multiple responses competing for control of action in trials. The N2 is one functionally-related cognitive control index for response conflict. And yet the underlying whiter matter neural substrates of inter-individual difference in conflict N2 remain unclear. So the aim of ...

journal_title：Brain research

authors： Gao S,Liu P,Guo J,Zhu Y,Liu P,Sun J,Yang X,Qin W

更新日期：2017-12-01 00:00:00

abstract：:It is suggested that altered neuroplasticity contributes to the pathophysiology of schizophrenia and antipsychotics may exhibit some of their therapeutic efficacies by improving neurogenesis and/or proliferation of neural progenitors. The aim of this study is to investigate whether chronic antipsychotics treatment aff...

journal_title：Brain research

authors： Chikama K,Yamada H,Tsukamoto T,Kajitani K,Nakabeppu Y,Uchimura N

更新日期：2017-12-01 00:00:00

abstract：:Primary open angle glaucoma (POAG) is a leading cause of irreversible blindness worldwide. Previous MRI studies have revealed that POAG can be associated with alterations in hippocampal function. Thus, the aim of this study was to investigate a relationship between chronic high intraocular pressure (IOP) and hippocamp...

journal_title：Brain research

authors： Yuan Y,Chen Z,Li L,Li X,Xia Q,Zhang H,Duan Q,Zhao Y

更新日期：2017-11-15 00:00:00

abstract：:Vagus nerve stimulation (VNS) has been used for years to treat patients with drug-resistant epilepsy. In the present study, the effect of different stimulation protocols of VNS on the hippocampal formation (HPC) type II theta field potentials were evaluated in anesthetized rats. The following theta parameters were ana...

journal_title：Brain research

authors： Broncel A,Bocian R,Kłos-Wojtczak P,Konopacki J

更新日期：2017-11-15 00:00:00

abstract：:Previous studies focusing on the relationship between lateralization of language function and age suffer from lack of a balanced distribution of age and handedness among participants, especially in the extremes of age. This limits our understanding of the influence of these factors on lateralization of language circui...

journal_title：Brain research

authors： Nenert R,Allendorfer JB,Martin AM,Banks C,Vannest J,Holland SK,Szaflarski JP

更新日期：2017-11-01 00:00:00

abstract：:Electroacupuncture (EA) has been reported to alleviate motor deficits in Parkinson's disease (PD) patients, and PD animal models. However, the mechanisms by which EA improves motor function have not been investigated. We have employed a 6-hydroxydopamine (6-OHDA) unilateral injection induced PD model to investigate wh...

journal_title：Brain research

authors： Li M,Li L,Wang K,Su W,Jia J,Wang X

更新日期：2017-10-15 00:00:00

abstract：:To investigate whether tactile spatial attention is modulated by perceptual load, behavioural and electrophysiological measures were recorded during two spatial cuing tasks in which the difficulty of the target/non-target discrimination was varied (High and Low load tasks). Moreover, to study whether attentional modul...

journal_title：Brain research

authors： Gherri E,Berreby F

更新日期：2017-10-15 00:00:00

abstract：:Our previous studies demonstrated that Austrolebias charrua annual fish is an excellent model to study adult brain cell proliferation and neurogenesis due to the presence of active and fast neurogenesis in several regions during its short lifespan. Our main goal was to identify and localize the cells that compose the ...

journal_title：Brain research

authors： Torres-Pérez M,Rosillo JC,Berrosteguieta I,Olivera-Bravo S,Casanova G,García-Verdugo JM,Fernández AS

更新日期：2017-10-15 00:00:00

abstract：:The effects of glucagon like peptide-1 (GLP-1) on reflex swallowing were examined using anaesthetized rats. GLP-1 was injected into the dorsal vagal complex (DVC) using glass micropipettes. Swallowing was induced by repeated electrical stimulation of the central cut end of the superior laryngeal nerve (SLN) and was id...

journal_title：Brain research

authors： Kobashi M,Mizutani S,Fujita M,Mitoh Y,Shimatani Y,Matsuo R

更新日期：2017-09-15 00:00:00

abstract：:Traumatic brain injury (TBI) contributes to morbidity in children, and more boys experience TBI. Cerebral autoregulation is impaired after TBI, contributing to poor outcome. Cerebral Perfusion Pressure (CPP) is often normalized by use of vasoactive agents to increase mean arterial pressure (MAP). In prior studies of n...

journal_title：Brain research

authors： Curvello V,Hekierski H,Pastor P,Vavilala MS,Armstead WM

更新日期：2017-09-01 00:00:00

abstract：:Neurotrophins regulate many aspects of neuronal function and activity. Specifically, the binding of Brain-derived neurotrophic factor (BDNF) to Tyrosine receptor kinase-B (TrkB) or its truncated version, TrkB-T1, can cause growth and differentiation or dominant inhibition of receptor signaling, respectively. There is ...

journal_title：Brain research

authors： Brague JC,Swann JM

更新日期：2017-08-15 00:00:00

abstract：:Cell transplantation using ventral mesencephalic tissue is an experimental approach to treat Parkinson's disease. This approach is limited by poor survival of the transplants and the high number of dopaminergic neurons needed for grafting. Increasing the yield of dopaminergic neurons in donor tissue is of great import...

journal_title：Brain research

authors： Seiler S,Di Santo S,Sahli S,Andereggen L,Widmer HR

更新日期：2017-08-01 00:00:00

abstract：:Ferulic acid (FA) has an important effect on scavenging free radicals, which is related to the alleviation of various neurodegenerative diseases. However, there are few studies about its effects on vascular dementia. In this study, we demonstrated the effect of FA on oxidative damage of brain microvascular endothelial...

journal_title：Brain research

authors： Chen JL,Duan WJ,Luo S,Li S,Ma XH,Hou BN,Cheng SY,Fang SH,Wang Q,Huang SQ,Chen YB

更新日期：2017-07-01 00:00:00

abstract：:This study describes the localization of [D-Leu-4]-OB3 and MA-[D-Leu-4]-OB3, synthetic peptide leptin mimetics, in the hypothalamus of Swiss Webster and C57BL/6J wild-type mice, leptin-deficient ob/ob mice, and leptin-resistant diet-induced obese (DIO) mice. The mice were given [D-Leu-4]-OB3 or MA-[D-Leu-4]-OB3 in 0.3...

journal_title：Brain research

authors： Anderson BM,Jacobson L,Novakovic ZM,Grasso P

更新日期：2017-06-01 00:00:00

abstract：:Facial allodynia is a migraine symptom that is generally considered to represent a pivotal point in migraine progression. Treatment before development of facial allodynia tends to be more successful than treatment afterwards. As such, understanding the underlying mechanisms of facial allodynia may lead to a better und...

journal_title：Brain research

authors： Wieseler J,Ellis A,McFadden A,Stone K,Brown K,Cady S,Bastos LF,Sprunger D,Rezvani N,Johnson K,Rice KC,Maier SF,Watkins LR

更新日期：2017-06-01 00:00:00

abstract：:Previous studies using a three-stimulus oddball task have shown the amplitude of P3a elicited by distractor stimuli increases when perceptual discrimination between standard and target stimuli becomes difficult. This means that the attentional capture by the distractor stimuli is enhanced along with an increase in tas...

journal_title：Brain research

authors： Sugimoto F,Katayama J

更新日期：2017-06-01 00:00:00

abstract：:Transient ischemic attack (TIA) has received only little attention in the experimental research field. Recently, we introduced a TIA model for mice, and here we set similar principles for simulating this human condition in Wistar rats. In the model: 1) transient nature of the event is ensured, and 2) 24h after the eve...

journal_title：Brain research

authors： Durukan Tolvanen A,Tatlisumak E,Pedrono E,Abo-Ramadan U,Tatlisumak T

更新日期：2017-05-15 00:00:00

abstract：:We previously reported that oral l-citrulline (l-Cit) administration antagonizes neuronal cell death in hippocampus following transient brain ischemia and that oral glutathione (GSH) administration prevents neuronal death through antioxidant activity. Here, we tested potential synergy of combined l-Cit and GSH adminis...

journal_title：Brain research

authors： Matsuo K,Yabuki Y,Fukunaga K

更新日期：2017-05-15 00:00:00

abstract：:Erythropoietin (EPO), a hematopoietic hormonal cytokine induced in response to hypoxia, has neuroprotective effects. EPO receptor (EPOR) is expressed in microglia, resident immune cells in the brain. However, the effect of EPO on microglial activation is not clear. In the present study, we demonstrated that the EPOR i...

journal_title：Brain research

authors： Tamura T,Aoyama M,Ukai S,Kakita H,Sobue K,Asai K

更新日期：2017-05-01 00:00:00

abstract：:Neurodegenerative disorders have attracted attention in last decades due to their high incidence in the world. The p53/miR-34a axis triggers apoptosis and suppresses viability in multiple types of cells, but little is known about its role in neurodegenerative diseases. In this study, we showed that presenilin (PS)-2, ...

journal_title：Brain research

authors： Li LH,Tu QY,Deng XH,Xia J,Hou DR,Guo K,Zi XH

更新日期：2017-05-01 00:00:00

abstract：:Our purpose was to investigate the cortical information processing of autobiographical fact violation (AFV) in self-referential questions. We expected that AFV in a self-referential question would evoke a characteristic pattern of neural synchrony and event-related potentials (ERPs). Averaged ERP and event-related syn...

journal_title：Brain research

authors： Choi JW,Cha KS,Jung KY,Kim KH

更新日期：2017-05-01 00:00:00

abstract：:Increased alcohol consumption and heightened aggression have been linked to social isolation. Furthermore, animals treated with alcohol following social separation showed higher aggression together with lower serotonin transmission. Although reduced serotonin transmission in the brain may be related to alcohol-induced...

journal_title：Brain research

authors： Mamiya PC,Matray-Devoti J,Fisher H,Wagner GC

更新日期：2017-05-01 00:00:00

abstract：:The accumulation of amyloid-β (Aβ) peptides in the brain of Alzheimer disease patients is associated to cognitive deficit, increased oxidative stress, and alterations in the circadian rhythms. Brain-derived neurotrophic factor (BDNF) and Neurogranin (RC3), play an important role in the synaptic plasticity underlying m...

journal_title：Brain research

authors： Navigatore-Fonzo L,Castro A,Pignataro V,Garraza M,Casais M,Anzulovich AC

更新日期：2017-04-01 00:00:00

abstract：:Ghrelin can alleviate cancer chemotherapy-induced dyspepsia in rodents, though the neural mechanisms involved are not known. Therefore, ghrelin projections from the lateral hypothalamus (LH) and its involvement in the regulation of gastric motility in cisplatin-treated rats were investigated with a multi-disciplined a...

journal_title：Brain research

authors： Gong Y,Liu Y,Liu F,Wang S,Jin H,Guo F,Xu L

更新日期：2017-03-15 00:00:00

abstract：:The stress-hyperresponsive Wistar-Kyoto (WKY) rat strain exhibits a hyperalgesic phenotype and is a useful genetic model for studying stress-pain interactions. Peroxisome proliferator-activated receptor (PPAR) signalling in the midbrain periaqueductal grey (PAG) modulates pain. This study characterised PPAR signalling...

journal_title：Brain research

authors： Okine BN,Gaspar JC,Madasu MK,Olango WM,Harhen B,Roche M,Finn DP

更新日期：2017-02-15 00:00:00